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918431-87-5

BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)-

    Cas No: 918431-87-5

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  • 918431-87-5 Structure

  • Basic information

    1. Product Name: BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)-
    2. Synonyms:
    3. CAS NO:918431-87-5
    4. Molecular Formula: C21H29Cl2FN2O2
    5. Molecular Weight: 431.3715632
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 918431-87-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 510.1°C at 760 mmHg
    3. Flash Point: 262.3°C
    4. Appearance: /
    5. Density: 1.25g/cm3
    6. Vapor Pressure: 1.6E-10mmHg at 25°C
    7. Refractive Index: 1.562
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)-(918431-87-5)
    12. EPA Substance Registry System: BenzaMide, 3,5-dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-diMethyl-2H-pyran-4-yl)Methyl]-4-piperidinyl]Methyl]-, (+)-(918431-87-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 918431-87-5(Hazardous Substances Data)

918431-87-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 918431-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,4,3 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 918431-87:
(8*9)+(7*1)+(6*8)+(5*4)+(4*3)+(3*1)+(2*8)+(1*7)=185
185 % 10 = 5
So 918431-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H29Cl2FN2O2/c1-20(2)12-15(3-8-28-20)13-26-6-4-21(24,5-7-26)14-25-19(27)16-9-17(22)11-18(23)10-16/h9-11,15H,3-8,12-14H2,1-2H3,(H,25,27)

918431-87-5Downstream Products

918431-87-5Relevant articles and documents

Design, synthesis, and evaluation of a novel 4-aminomethyl-4- fluoropiperidine as a T-type Ca2+ channel antagonist

Shipe, William D.,Barrow, James C.,Yang, Zhi-Qiang,Lindsley, Craig W.,Yang, F. Vivien,Schlegel, Kelly-Ann S.,Shu, Youheng,Rittle, Kenneth E.,Bock, Mark G.,Hartman, George D.,Tang, Cuyue,Ballard, Jeanine E.,Kuo, Yuhsin,Adarayan, Emily D.,Prueksaritanont, Thomayant,Zrada, Matthew M.,Uebele, Victor N.,Nuss, Cindy E.,Connolly, Thomas M.,Doran, Scott M.,Fox, Steven V.,Kraus, Richard L.,Marino, Michael J.,Graufelds, Valerie Kuzmick,Vargas, Hugo M.,Bunting, Patricia B.,Hasbun-Manning, Martha,Evans, Rose M.,Koblan, Kenneth S.,Renger, John J.

scheme or table, p. 3692 - 3695 (2009/04/07)

The novel T-type antagonist (S)-5 has been prepared and evaluated in in vitro and in vivo assays for T-type calcium ion channel activity. Structural modification of the piperidine leads 1 and 2 afforded the fluorinated piperidine (S)-5, a potent and selec

4-FLUORO-PIPERIDINE T-TYPE CALCIUM CHANNEL ANTAGONISTS

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Page/Page column 26, (2010/11/25)

The present invention is directed to 4-fluoro-piperidine compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which T-type calcium channel

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