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5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE is a pyrrolopyridine derivative with the molecular formula C16H26ClN2Si. It features a chloro substituent and a triisopropylsilyl group attached to the nitrogen atom, giving it unique structural characteristics. This chemical compound holds potential in medicinal chemistry due to its distinctive attributes and possible biological activities, making it a promising candidate for use in the synthesis of pharmaceuticals and agrochemicals. Its silicon-containing group also suggests potential applications in materials science and chemical research.

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  • 918523-59-8 Structure
  • Basic information

    1. Product Name: 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE
    2. Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-1-[tris(1-methylethyl)silyl]-
    3. CAS NO:918523-59-8
    4. Molecular Formula: C16H25ClN2Si
    5. Molecular Weight: 308.93
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 918523-59-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 320.5°C at 760 mmHg
    3. Flash Point: 147.6°C
    4. Appearance: /
    5. Density: 1.05g/cm3
    6. Vapor Pressure: 0.000316mmHg at 25°C
    7. Refractive Index: 1.534
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE(918523-59-8)
    12. EPA Substance Registry System: 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE(918523-59-8)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 918523-59-8(Hazardous Substances Data)

918523-59-8 Usage

Uses

Used in Medicinal Chemistry:
5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, leveraging its unique structure and potential biological activities to contribute to the development of new therapeutic agents.
Used in Materials Science:
The silicon-containing group in 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE makes it a candidate for use in materials science, where its properties can be explored for potential applications in the creation of new materials or the enhancement of existing ones.
Used in Chemical Research:
5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE is utilized in chemical research to further understand its properties and potential uses, as its unique structure may offer new insights and directions for scientific exploration.
Note: Since the provided materials do not specify particular applications or industries for 5-CHLORO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE, the uses listed are general and based on the potential inferred from its description. Further research would be necessary to identify specific applications and industries.

Check Digit Verification of cas no

The CAS Registry Mumber 918523-59-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,5,2 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 918523-59:
(8*9)+(7*1)+(6*8)+(5*5)+(4*2)+(3*3)+(2*5)+(1*9)=188
188 % 10 = 8
So 918523-59-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H25ClN2Si/c1-11(2)20(12(3)4,13(5)6)19-8-7-14-9-15(17)10-18-16(14)19/h7-13H,1-6H3

918523-59-8 Well-known Company Product Price

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  • Aldrich

  • (ADE000924)  5-Chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine  AldrichCPR

  • 918523-59-8

  • ADE000924-1G

  • 7,411.95CNY

  • Detail

918523-59-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane

1.2 Other means of identification

Product number -
Other names A-6708

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:918523-59-8 SDS

918523-59-8Relevant articles and documents

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

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Page/Page column 35, (2008/12/06)

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

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Page/Page column 105, (2010/11/25)

Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

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