918644-73-2

Basic information

• Product Name: 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester
• Synonyms: 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester;3-Azaspiro[5.5]undecane-3-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester;tert-butyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylate;3-BOC-9-HYDROXY-3-AZASPIRO[5.5]UNDECANE
• CAS NO: 918644-73-2
• Molecular Formula: C₁₅H₂₇NO₃
• Molecular Weight: 269.37978
• Mol File: 918644-73-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester(918644-73-2)
• EPA Substance Registry System: 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester(918644-73-2)

Safety Data

• Hazardous Substances Data: 918644-73-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester serves as a building block for the synthesis of biologically active molecules, contributing to the development of new drug candidates due to its unique structural features and potential for modification.
Used in Drug Discovery:
As a component in drug discovery, 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester is used for its potential to contribute to the creation of novel pharmaceutical compounds with therapeutic applications.
Used in Medicinal Chemistry:
In medicinal chemistry, 9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester is employed as a key intermediate in the synthesis of complex molecules with potential medicinal properties, facilitating the advancement of new treatment options for various medical conditions.
Used in Development of New Treatments:
9-Hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester may have potential use in the development of new treatments for a range of medical conditions, leveraging its unique chemical structure to target specific biological pathways or mechanisms of disease.

Upstream product

• 873924-08-4 9-oxo-3-azaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester 

Downstream Products

• 918644-74-3 9-(3,4-dichloro-phenoxy)-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester 
• 1272758-41-4 9-amino-3-azaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester 
• 873924-08-4 9-oxo-3-azaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Nitroimidazole compound as well as preparation method and application thereof

The invention discloses a novel nitroimidazole compound as well as a preparation method and application thereof. The nitroimidazole compound has a general formula (I) shown in the specification.

SPIROCYCLIC COMPOUNDS

Described herein are compounds of formula (I) (Formula (I)). The compounds of formula (I) act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

Substituted Disulfonamide Compounds

Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

Substituted Indole Compounds

Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).

Substituted Spiroamide Compounds

Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).

Substituted Spiro-amide Compounds

Substituted spiro-amide compounds corresponding to formula I in which R5 through R8, D, X, Y and Z have defined meanings, processes for preparing such spiro-amide compounds, pharmaceutical compositions containing such compounds, and methods of using such spiro-amide compounds for treating and/or inhibiting disorders or disease states mediated at least in part by the bradykinin 1 receptor.

SUBSTITUTED BENZIMIDAZOLES, BENZOTHIAZOLES AND BENZOXAZOLES

The present invention relates to substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.

NOVEL 3-AZA-SPIRO[5.5]UNDECANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

This invention relates to novel 3-aza-spiro[5.5]undecane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions