919016-93-6

Basic information

• Product Name: 4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID
• Synonyms: 4-(3-FLUOROPHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXYLIC ACID;4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID;4-(3-FLUOROPHENYL)OXANE-4-CARBOXYLIC ACID;2H-Pyran-4-carboxylic acid, 4-(3-fluorophenyl)tetrahydro-
• CAS NO: 919016-93-6
• Molecular Formula: C₁₂H₁₃FO₃
• Molecular Weight: 224.2282232
• Mol File: 919016-93-6.mol

Chemical Properties

• Appearance: /
• Refractive Index: 1.536
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID(919016-93-6)
• EPA Substance Registry System: 4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID(919016-93-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 919016-93-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-(3-Fluoro-phenyl)-tetrahydro-pyran-4-carboxylic acid is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of molecules with potential applications in different industries.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 4-(3-Fluoro-phenyl)-tetrahydro-pyran-4-carboxylic acid is used as a key building block in the development of new drugs. Its incorporation into molecular frameworks can lead to the discovery of novel bioactive compounds with therapeutic potential. The specific properties and applications of 4-(3-FLUORO-PHENYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID in medicinal chemistry would require further investigation and optimization in a laboratory setting to fully realize its potential.

InChI:InChI=1/C12H13FO3/c13-10-3-1-2-9(8-10)12(11(14)15)4-6-16-7-5-12/h1-3,8H,4-7H2,(H,14,15)

Upstream product

• 501-00-8 3-fluorophenylacetonitrile 
• 1035261-79-0 4-(3-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile 

Downstream Products

• 1040860-83-0 4-(3-fluorophenyl)-tetrahydro-2H-pyran-4-carboxylic acid chloride 
• 1035261-80-3 diethyl 2-(4-(3-fluorophenyl)-tetrahydro-2H-pyran-4-carbonyl)malonate 

Relevant articles and documents

PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS

The present invention relates to novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as prostaglandin E2 (PGE2) EP4 receptor antagonists, which renders them highly advantageous for use in therapy, particularly in the treatment or prevention of cancer, a neovascular eye disease, inflammatory pain, or an inflammatory disease, such as, e.g., multiple sclerosis, rheumatoid arthritis or endometriosis.

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.