Aryl indanyl ketones: Efficient inhibitors of the human peptidyl prolyl cis/trans isomerase pin1
A good imitation: Aryl-1-indanyl ketones are found to be highly efficient, reversible, cell-penetrating inhibitors of the human peptidyl prolyl cis/trans isomerase Pin1. Owing to their structure 1, they are assumed to mimic the transition state 2 of the e