- SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
-
Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.
- -
-
Page/Page column 368; 369
(2014/09/29)
-
- SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
-
Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.
- -
-
Page/Page column 0283; 0284
(2014/09/30)
-
- SUBSTITUTED PYRIDINE DERIVATIVES AS FABI INHIBITORS
-
The present invention provides substituted pyridine derivatives of formula (I), which may be therapeutically useful as as anti-bacterial agents, more particulalrly FabI inhibitors. Formula(I) in which R1 to R5 and L have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage anti-bacterial agents, more particularly FabI inhibitors. The present invention also provides methods for synthesizing and administering the FabI inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the FabI inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.
- -
-
Page/Page column 37
(2013/06/27)
-