Compounds of the formula STR1 wherein R1, R2, R3, and A are as described herein, are set forth. These compounds are useful as anti-allergic agents and agents for the treatment of cardiovascular diseases.
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(2008/06/13)
DERIVATIVES OF 4-ACETYL-3-HYDROXY-2-ALKYL-PHENOXYCARBOXYLIC ACIDS
The invention relates to compounds of the formula STR1 wherein R is hydrogen or lower alkyl, Y is alkylene; Z is alkylene, STR2 the asterisk herein denotes bonding to the substituted acetophenone; R 2 is hydrogen or lower alkoxy; and n is an integer of 1
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(2008/06/13)
Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives
A series of derivatives of 2,4-dihydroxy-3-propylacetophenone were prepared and examined for their ability to block leukotriene D4 (LTD4) induced contraction of guinea pig ileum. Straight-chain carboxylic acids where the carboxyl gro
This invention provides novel alkane derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.
The invention relates to compounds of the formula STR1 wherein R is hydrogen or lower alkyl, Z is alkylene of 1 to 10 carbon atoms, --(C*H2)3 --C C--, --C*H2 --C C--(CH2)3 --, and --(CH2)s
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(2008/06/13)
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