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925252-83-1

2-(1-NAPHTHYL)ACETAMIDOXIME is a chemical compound that belongs to the class of oximes, which are organic compounds that contain the functional group C=N-OH. This particular compound is derived from 1-naphthylacetic acid and hydroxylamine and has a molecular formula C12H10N2O. It is commonly used as a pharmaceutical intermediate and has been studied for its potential pharmacological properties, such as its ability to inhibit the activity of certain enzymes. Additionally, it has been shown to have antioxidant properties and may have applications in the development of new drugs or treatments for various medical conditions.

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  • 925252-83-1 Structure

  • Basic information

    1. Product Name: 2-(1-NAPHTHYL)ACETAMIDOXIME
    2. Synonyms: BUTTPARK 37\11-75;2-(1-NAPHTHYL)ACETAMIDOXIME;2-(NAPHTH-1-YL)ACETAMIDE OXIME;N'-hydroxy-2-(1-naphthyl)ethanimidamide;2-(1-Naphthyl)Acetamidoxime(WX690146)
    3. CAS NO:925252-83-1
    4. Molecular Formula: C12H12N2O
    5. Molecular Weight: 200.24
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 925252-83-1.mol

  • Chemical Properties

    1. Melting Point: 108-111
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(1-NAPHTHYL)ACETAMIDOXIME(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(1-NAPHTHYL)ACETAMIDOXIME(925252-83-1)
    11. EPA Substance Registry System: 2-(1-NAPHTHYL)ACETAMIDOXIME(925252-83-1)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 925252-83-1(Hazardous Substances Data)

925252-83-1 Usage

Uses

Used in Pharmaceutical Industry:
2-(1-NAPHTHYL)ACETAMIDOXIME is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its ability to inhibit the activity of certain enzymes makes it a valuable component in the development of new treatments for various medical conditions.
Used in Antioxidant Applications:
2-(1-NAPHTHYL)ACETAMIDOXIME is used as an antioxidant in the development of new drugs or treatments for various medical conditions. Its antioxidant properties can help protect cells from damage caused by reactive oxygen species and may contribute to the prevention or treatment of diseases associated with oxidative stress.

Check Digit Verification of cas no

The CAS Registry Mumber 925252-83-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,5,2,5 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 925252-83:
(8*9)+(7*2)+(6*5)+(5*2)+(4*5)+(3*2)+(2*8)+(1*3)=171
171 % 10 = 1
So 925252-83-1 is a valid CAS Registry Number.

925252-83-1Upstream product

925252-83-1Downstream Products

925252-83-1Relevant articles and documents

Synthesis of 4,5-dihydro 1,2,4-oxadiazoles from N-unsubstituted amidoximes

Lessel,Herfs

, p. 22 - 26 (2007/10/03)

4,5-Dihydro 1,2,4-oxadiazoles can be synthesized from aromatic and araliphatic amidoximes by cyclocondensation with aldehydes and ketones. Resulting heterocycles differ in substitution at C-3 and C-5 showing the scope of the simple reaction.

Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70

Vu, Chi B.,Corpuz, Evelyn G.,Merry, Taylor J.,Pradeepan, Selvaluxmi G.,Bartlett, Catherine,Bohacek, Regine S.,Botfield, Martyn C.,Eyermann, Charles J.,Lynch, Berkley A.,MacNeil, Ian A.,Ram, Mary K.,Van Schravendijk, Marie Rose,Violette, Shelia,Sawyer, Tomi K.

, p. 4088 - 4098 (2007/10/03)

A series of 1,2,4-oxadiazole analogues has been shown to be potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70, a potential therapeutic target for immune suppression. These compounds typically are 200- 400-fold more potent than the native,

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