925932-14-5Relevant articles and documents
A NEW SYNTHESIS OF α-AMINO ACIDS (E)-β,γ-ENOL ETHERS
Daumas, M.,Vo-Quang, L.,Vo-Quang, Y.,le Goffic, F.
, p. 5121 - 5124 (1989)
Various N-protected amino acids bearing an enol ether side chain were synthesized by a new method allowing a great versatility in the introduction of both the N-protective groups and the enol ether moieties.This method deals with a Wittig-Horner condensat
New non-proteogenic aminoacids bearing an enol aryl-ether moiety
Daumas,Vo-Quang,Le Goffic
, p. 2373 - 2384 (2007/10/02)
Aminoacids bearing an enol aryl-ether moiety have been synthesized by a new method allowing a great versatility in the introduction of N-protective groups and enol ether functions. This method involves a Wittig-Horner condensation affording alpha, beta-dehydrohomoserine ether derivatives, followed by a regio and stereoselective isomerization into the desired E enol ether. Clean deprotection was achieved providing new 2-amino-4-aryloxybut-3(E)-enoic acids 3.