Effect of stereochemistry of Δlac-acetogenins on the inhibition of?mitochondrial complex I (NADH-ubiquinone oxidoreductase)
Δlac-Acetogenins are a new type of inhibitors of bovine heart mitochondrial complex I (NADH-ubiquinone oxidoreductase). We synthesized a series of Δlac-acetogenins in which the stereochemistry around the hydroxylated tetrahydrofuran (THF) ring moiety was
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