926214-73-5 Usage
Chemical structure
The compound consists of a cyclobutane ring attached to a piperidine ring and a carboxylic acid group.
Cyclobutane ring
A four-membered ring that is less stable than larger rings and can impart unique properties to the molecules it is attached to.
Piperidine ring
A common structural motif in many biologically active compounds, making this chemical of interest in the development of new pharmaceuticals.
Carboxylic acid group
Allows for further derivatization and modification of the molecule for specific applications.
Pharmaceutical research and drug development
The compound is commonly used in these fields due to its potential as a building block in the synthesis of various biologically active compounds.
Biological activity
The presence of the piperidine ring, a common structural motif in many biologically active compounds, suggests that this chemical may have potential applications in the development of new drugs.
Derivatization
The carboxylic acid group present in the molecule enables further chemical modifications, which can be useful for tailoring the compound's properties for specific applications.
Synthesis
As a building block, this compound can be used in the synthesis of a wide range of biologically active molecules, contributing to the development of new pharmaceuticals and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 926214-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,6,2,1 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 926214-73:
(8*9)+(7*2)+(6*6)+(5*2)+(4*1)+(3*4)+(2*7)+(1*3)=165
165 % 10 = 5
So 926214-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO3/c13-10(8-3-1-4-8)12-6-2-5-9(7-12)11(14)15/h8-9H,1-7H2,(H,14,15)
926214-73-5Relevant articles and documents
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists
Lamb, Jeffrey P.,Engers, Darren W.,Niswender, Colleen M.,Rodriguez, Alice L.,Venable, Daryl F.,Conn, Jeffrey P.,Lindsley, Craig W.
, p. 2711 - 2714 (2011/06/20)
This Letter describes a chemical lead optimization campaign directed at a weak mGlu5 NAM discovered while developing SAR for the mGlu 5 PAM, ADX-47273. An iterative parallel synthesis effort discovered multiple, subtle molecular switches that afford potent mGlu5 NAMs, mGlu5 PAMs as well as mGlu5 partial antagonists.
