cas 926226-20-2, 7-hydroxy-2H-chromene-3-carbaldehyde | Articles data ｜lookchem

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926226-20-2

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Towards a library of chromene cannabinoids: A combinatorial approach on solid supports
A novel solid-phase synthesis towards classical cannabinoids is presented. Starting from immobilized salicylaldehydes the desired THC-analogous tricycles are obtained in four atom-economic steps including cleavage. The reagents of the employed reactions (domino oxa-Michael-aldol, Wittig, and Diels-Alder) can be varied easily, providing the basis for a combinatorial approach. Overall yields range from 20-60%. Georg Thieme Verlag Stuttgart New York.
Kapeller, Dagmar C.,Br?se, Stefan
p. 161 - 164
(2011/03/19)

More Articles about upstream products of 926226-20-2

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1228581-34-7
7-{[4-(trifluoromethyl)phenyl]ethynyl}-2H-chromene-3-carbaldehyde

Chemical Properties

Melting Point: 191-201 °C(Solv: dichloromethane (75-09-2); ethyl acetate (141-78-6))
Boiling Point: 381.4±42.0 °C(Predicted)
Density: 1.425±0.06 g/cm3(Predicted)
PKA: 9.16±0.20(Predicted)

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