Synthesis and antimalarial activity of new isotebuquine analogues
Amodiaquine (AQ) and tebuquine are 4-aminoquinoline antimalarials with Mannich base side chain and are highly effective against chloroquine (CQ)-resistant strains of Plasmodium falciparum. Clinical use of AQ has been severely restricted due to hepatoxicit
Miroshnikova, Olga V.,Hudson, Thomas H.,Gerena, Lucia,Kyle, Dennis E.,Lin, Ai J.
p. 889 - 896
(2007/10/03)
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