928653-80-9 Usage
Uses
Used in Organic Synthesis:
5-BROMO-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with diverse properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-BROMO-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER is used as a precursor for the development of pharmaceuticals and bioactive molecules. Its versatile chemical properties make it a valuable component in the design and synthesis of new drugs.
Used in Pharmaceutical Industry:
5-BROMO-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER is used as a key intermediate in the production of various pharmaceuticals. Its presence in the synthesis process contributes to the development of new medications with potential therapeutic benefits.
Used in Research and Development:
In research and development settings, 5-BROMO-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER is used as a valuable tool for studying the properties and potential applications of pyrrolopyridine-based compounds. Its unique structure provides insights into the design and synthesis of novel molecules with specific biological activities.
Overall, 5-BROMO-PYRROLO[2,3-B]PYRIDINE-1-CARBOXYLICACIDTERT-BUTYLESTER plays a significant role in various industries, particularly in the development of new pharmaceuticals and organic compounds. Its versatility and potential applications make it an important compound in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 928653-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,6,5 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 928653-80:
(8*9)+(7*2)+(6*8)+(5*6)+(4*5)+(3*3)+(2*8)+(1*0)=209
209 % 10 = 9
So 928653-80-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H13BrN2O2/c1-12(2,3)17-11(16)15-5-4-8-6-9(13)7-14-10(8)15/h4-7H,1-3H3
928653-80-9Relevant articles and documents
Method for preparing 5-hydroxy-7-azaindole
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Paragraph 0063-0066; 0084-0089; 0109-0112, (2017/12/28)
The invention discloses a method for preparing 5-hydroxy-7-azaindole. The intermediate structure is shown in the formula III. The method comprises that a compound 5-bromo-7-azaindole shown in the formula I as a raw material undergoes a nitrogen protection reaction and a hydroxylation and direct deprotection reaction to produce 5-hydroxy-7-azaindole shown in the formula III. The method utilizes cheap and easily available raw materials, realizes a low cost, is used under mild reaction conditions, has a high yield and is suitable for industrial large-scale production.
Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequence
Merkul, Eugen,Klukas, Fabian,Dorsch, Dieter,Graedler, Ulrich,Greiner, Hartmut E.,Mueller, Thomas J. J.
supporting information; experimental part, p. 5129 - 5136 (2011/09/13)
The one-pot, three-component Sonogashira coupling-TMS-deprotection-CuAAC ("click") sequence is the key reaction for the rapid synthesis of triazolyl substituted N-Boc protected NH-heterocycles, such as indole, indazole, 4-, 5-, 6-, and 7-azaindoles, 4,7-diazaindole, 7-deazapurines, pyrrole, pyrazole, and imidazole. Subsequently, the protective group was readily removed to give the corresponding triazolyl derivatives of these tremendously important NH-heterocycles. All compounds have been tested in a broad panel of kinase assays. Several compounds, 8f, 8h, 8k, and 8l, have been shown to inhibit the kinase PDK1, a target with high oncology relevance, and thus they are promising lead structures for the development of more active derivatives. The X-ray structure analysis of compound 8f in complex with PDK1 has revealed the detailed binding mode of the molecule in the kinase. The Royal Society of Chemistry 2011.
