A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives
A highly efficient and green method has been developed for the rapid preparation of highly functionalized isoxazolopyridin-3-amine derivatives in excellent yields. This process has a broad substrate scope, is operationally simple, and generally requires no chromatographic purification. In addition, the process is scalable and significantly greener than current alternatives with a PMI of 18 and water as the reaction solvent.
Yu, Wensheng,Bulger, Paul G.,Maloney, Kevin M.
p. 4941 - 4946
(2016/10/12)
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