92935-94-9Relevant articles and documents
Triangeliphthalides A-D: Bioactive phthalide trimers with new skeletons from: Angelica sinensis and their production mechanism
Zou, Jian,Chen, Guo-Dong,Zhao, Huan,Wang, Xiao-Xia,Zhang, Zai-Jun,Qu, Yi-Bo,He, Rong-Rong,So, Kwok-Fai,Yao, Xin-Sheng,Gao, Hao
supporting information, p. 6221 - 6224 (2019/06/07)
Triangeliphthalides A-D (1-4), four novel phthalide trimers with two new linkage styles, were isolated from Angelica sinensis, together with two related phthalide dimers (5-6). Their structures including absolute configurations were determined. The production mechanism of phthalide polymers was proposed, and their bioactivities were also evaluated.
Triligustilides A and B: Two Pairs of Phthalide Trimers from Angelica sinensis with a Complex Polycyclic Skeleton and Their Activities
Zou, Jian,Chen, Guo-Dong,Zhao, Huan,Huang, Ying,Luo, Xiang,Xu, Wei,He, Rong-Rong,Hu, Dan,Yao, Xin-Sheng,Gao, Hao
supporting information, p. 884 - 887 (2018/02/10)
Two pairs of enantiomeric phthalide trimers [(-)/(+) triligustilides A (1a/1b) and (-)/(+) triligustilides B (2a/2b)] with complex polycyclic skeletons simultaneously possessing bridged, fused, and spiro ring systems were isolated from Angelica sinensis, together with two pairs of new phthalide dimers. The biogenetic pathways of new phthalides were proposed, and their bioactivities were also evaluated. This is the first time optically pure polymeric phthalides have been obtained from racemates, and their absolute configurations are reported.