929626-18-6Relevant articles and documents
FLUORINATION OF ORGANIC COMPOUNDS
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Page/Page column 87, (2010/07/10)
Methods for fluorinating organic compounds are described herein.
Fluorination of boronic acids mediated by silver(I) Triflate
Furuya, Takeru,Ritter, Toblas
supporting information; experimental part, p. 2860 - 2863 (2009/12/05)
A regiospecific Ag-mediated fluorination reaction of aryl- and alkenylboronic acids and esters Is reported. The fluorination reaction uses commercially available reagents, does not require the addition of exogenous ligands, and can be performed on a multigram scale. This report discloses the first practical reaction sequence from arylboronic acid to aryl fluorides.
One-pot synthesis of arylboronic acids and aryl trifluoroborates by Ir-catalyzed borylation of arenes
Murphy, Jaclyn M.,Tzschucke, C. Christoph,Hartwig, John F.
, p. 757 - 760 (2007/10/03)
(Chemical Equation Presented) The synthesis of arylboronic acids and aryl trifluoroborates in a one-pot sequence by Ir-calalyzed borylation of arenes is reported. To prepare the arylboronic acids, the Ir-catalyzed borylation is followed by oxidative cleavage of the boronic ester with NaIO4. To prepare the aryltrifluoroborate, the Ir-catalyzed borylation is followed by displacement of pinacol by KHF2. These two-step sequences give products that are more reactive toward subsequent chemistry than the initially formed pinacol boronates.
Arenes to anilines and aryl ethers by sequential iridium-catalyzed borylation and copper-catalyzed coupling
Tzschucke, C. Christoph,Murphy, Jaclyn M.,Hartwig, John F.
, p. 761 - 764 (2007/10/03)
(Chemical Equation Presented) N-Alkyl- and N-arylanilines were synthesized from arenes by a two-step sequence of iridium-catalyzed borylation and copper-catalyzed coupling with amines. Diaryl ethers were obtained by a related sequence of arene borylation, followed by coupling with phenols. In particular, 3,5-disubstituted arylamines and aryl ethers were prepared by initiating this sequence with meta-substituted arenes.