Model studies for the synthesis of the antibiotic lactonamycin and the discovery of new reactions and mechanisms for the construction of substituted heterocycles
A new and highly efficient route for the construction of a model for the synthesis of lactonamycin 1 is reported. The chemistry has been utilised for the synthesis of heterocyclic rings, and new reactions for the synthesis of dienes and alkynes are report
Parsons, Philip J.,Board, Jonathan,Faggiani, Davide,Hitchcock, Peter B.,Preece, Lewis,Waters, Alexander J.
experimental part
p. 6526 - 6533
(2010/10/19)
A novel cyclisation strategy for the synthesis of lactonamycin: A new route to highly functionalised heterocyclic rings
A novel thermal cascade reaction equivalent to the well-known [2+2+2] cycloaddition has been developed which is clean and reliable and does not involve the use of metal ions. This highly efficient method has been used to construct a model for the synthesi
Parsons, Philip J.,Board, Johnathan,Waters, Alexander J.,Hitchcock, Peter B.,Wakenhut, Florian,Walter, Daryl S.
p. 3243 - 3246
(2008/09/17)
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