931-18-0

Basic information

• Product Name: PYRAZINE-2,3-DIOL
• Synonyms: PYRAZINE-2,3-DIOL;2,3-Pyrazinediol;1,4-Dihydropyrazine-2,3-dione;2,3-Dioxo-1,2,3,4-tetrahydropyrazine
• CAS NO: 931-18-0
• Molecular Formula: C₄H₄N₂O₂
• Molecular Weight: 112.09
• Mol File: 931-18-0.mol

Chemical Properties

• Melting Point: 300 °C
• Appearance: /
• CAS DataBase Reference: PYRAZINE-2,3-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: PYRAZINE-2,3-DIOL(931-18-0)
• EPA Substance Registry System: PYRAZINE-2,3-DIOL(931-18-0)

Safety Data

• Hazardous Substances Data: 931-18-0(Hazardous Substances Data)

Upstream product

• 923-97-7 N-(2-diethoxyethyl)oxamide 
• 160315-20-8 2-hydroxy-3-methoxypyrazine 
• 68468-30-4 trans-2,3-dimethoxypyrazine 
• 43029-19-2 2-amino-3-hydroxypyrazine 

Downstream Products

• 4858-85-9 2,3-dichloropyrazine 
• 33870-87-0 1,4-dibenzyl-1,4-dihydropyrazine-2,3-dione 

Relevant articles and documents

1, 3-dipolar cycloaddition reactions of benzonitrile oxide to 2(1II)-pyrazinone and its n- and o-methyl derivatives

2(1H)-Pyrazinone, which is in equilibrium with 2-pyrazinol, reacts with benzonitrile oxide (BNO) affording the N-adducl with a 67% yield, while 2-methoxypyrazine gives two methoxypyrazinones (ca. 3%) and a biscycloadduct together with its degradation product, which derive from the two unisolable monocycloadducts to the C=N4 double bond. Af-Methylpyrazinone gives only the degradation product (3.4%) of the initial monocycloadduct of BNO to C=N4: double bond.

Synthesis of Derivatives of Pyrazinopyridimidin-4-ones

3-Alkoxy-2-aminopyrazines have been condensed with ethyl ethoxymethylenemalonate and isopropylidene methoxymethylenemalonate to afford 9-alkoxypyrazinopyrimidin-4-ones substituted in the first case by an ethoxycarbonyl group at 3 position.