93181-85-2Relevant articles and documents
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy
Hallot,Brodin,Merlier,Brochard,Chambon,Biziere
, p. 369 - 375 (2007/10/02)
A series of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines derivatives was synthesized and evaluated for anticonvulsant activity. The compounds were screened in mice for their ability to antagonize maximal electroshock- and bicuculline-induced seizures;
Pyridazine and pyrimidine compounds active on the central nervous system as sedatives or anticonvulsants
-
, (2008/06/13)
The present invention relates to the compounds of formula STR1 in which X1 represents N or STR2 X2 represents N or STR3 provided that X1 and X2 are different from each other; R1 and R2 bein