Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity
A series of novel tylophorine-derived dibenzoquinolines has been synthesized and their biological activity evaluated. Three assays were conducted: inhibition of cancer cell proliferation, inhibition of TGEV replication for anticoronavirus activity, and su
A High-Yield Modification of the Pschorr Phenanthrene Synthesis
A relationship between substituents on the aryl ring undergoing homolytic aromatic substitution and the yield of Pschorr reaction product has been demonstrated.The new variation in which a (phenylsulfonyl)oxy group is present on the acceptor ring has been used to synthesize several highly oxygenated 9-phenanthrenecarboxylic acids in significantly improved yields.
Duclos, Richard I.,Tung, Jay S.,Rapoport, Henry
p. 5243 - 5246
(2007/10/02)
More Articles about upstream products of 93279-75-5