Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity
Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of indivi
Messina, Cynthia,Ottenwaelder, Xavier,Forgione, Pat
supporting information
p. 7348 - 7352
(2021/10/01)
INHIBITORS OF Akt ACTIVITY
Invented are novel thiophene compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.
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Page/Page column 160-161
(2010/11/27)
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