Pyrrolidine and iodine catalyzed domino aldol-Michael-dehydrogenative synthesis of flavones
A one pot synthesis of flavones is established from 2′- hydroxyacetophenones and substituted aromatic aldehydes. The method uses domino aldol-Michael-oxidation reaction catalyzed by pyrrolidine as a base and iodine as an oxidant in dimethyl sulfoxide.
Naik, Mayuri M.,Tilve, Santosh G.,Kamat, Vijayendra P.
Synthesis and Biological Evaluation of Substituted Flavones as Gastroprotective Agents
Flavone (1) was found to protect against ethanol-induced gastric damage in rats; however, it is known that certain compounds in the flavone class, including flavone itself, are inducers of hepatic drug metabolizing enzymes.With the hope identifying gastro
Ares, Jeffrey J.,Outt, Pamela E.,Randall, Jared L.,Murray, Peter D.,Weisshaar, Pamela S.,et al.
p. 4937 - 4943
(2007/10/03)
More Articles about upstream products of 93321-62-1