93343-11-4

Basic information

• Product Name: 2,4,6-TRIFLUOROTOLUENE
• Synonyms: 2,4,6-TRIFLUOROTOLUENE;Benzene, 1,3,5-trifluoro-2-methyl- (9CI);2-Methyl-1,3,5-trifluorobenzene;2,4,6-Trifluorotolune
• CAS NO: 93343-11-4
• Molecular Formula: C7H5F3
• Molecular Weight: 146.11
• Product Categories: HALIDE;Halogen toluene
• Mol File: 93343-11-4.mol

Chemical Properties

• Boiling Point: 105-110
• Flash Point: 12.6 °C
• Appearance: /
• Density: 1.234 g/cm³
• CAS DataBase Reference: 2,4,6-TRIFLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIFLUOROTOLUENE(93343-11-4)
• EPA Substance Registry System: 2,4,6-TRIFLUOROTOLUENE(93343-11-4)

Safety Data

• Hazard Codes: F
• Hazardous Substances Data: 93343-11-4(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
2,4,6-Trifluorotoluene is used as a starting material for the synthesis of various chemical products due to its reactivity in nucleophilic aromatic substitutions. This property enables the creation of a wide range of valuable compounds for different applications.
Used as a Solvent:
In the chemical industry, 2,4,6-trifluorotoluene serves as a solvent for various chemical processes. Its volatility and compatibility with certain types of reactions make it a suitable choice for dissolving and facilitating the interaction of reactants.
Used in Environmental Management:
Given the persistence of 2,4,6-trifluorotoluene as a fluorinated compound, it is also used in the development of strategies for its safe disposal and handling to minimize environmental impact. This includes the design of methods for containment, treatment, and safe disposal to prevent contamination.

Upstream product

• 372-38-3 1,3,5-trifluorobenzene 
• 74-88-4 methyl iodide 

Relevant articles and documents

REACTIONS OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. REACTION OF POLYFLUORINATED DERIVATIVES OF BENZENE WITH SODIUM AMIDE

Under the influence of sodium amide in liquid ammonia at a temperature no higher than -33 deg C pentafluorobenzene, 1,2,4,5-tetrafluorobenzene, and 1,3-difluorobenzene undergo deprotonation with the formation of fluorinated phenyl anions, which are resistant to the elimination of a fluoride ion and can be detected by the formation of the products from interaction with electrophiles (with the initial compound in the first case and with methyl iodide in the other two cases). 1,3,5-Trifluorobenzene behaves similarly in reaction with one equivalent of sodium amide, but with two equivalents of sodium amide this compound and 1,2,3,5-tetrafluorob enzene undergo substitution of a fluorine atom by an amino group with the formation of 3,5-di- and 3,4,5-trifluoroanilines respectively.This is clearly due to the double deprotonation of these compounds with the formation of polyfluorinated m-phenylene dianions, which are then converted with the elimination of a fluoride ion into the corresponding dehydrophenyl anions.

REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA IV.* THE NUCLEOPHILIC AND PROTOPHILIC ACTIVITY OF METHOXIDE AND HYDROXIDE IONS IN REACTIONS WITH POLYFLUORINATED AROMATIC COMPOUNDS

In the reaction of polyfluorinated derivatives of benzene with potassium methoxide in liquid ammonia a fluorine atom is substituted by a methoxy group.With potassium hydroxide reactions involving removal of a proton from a ring carbon atom take place preferentially.The possibility of polyfluoroarylation and methylation catalyzed by potassium hydroxide in polyfluorinated aromatic compounds, based on capture of the polyflurinated aryl anion by the electrophile, was demonstrated.