- New synthetic routes to 1,3,4-thiadiazole derivatives
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Different new 1,3,4-thiadiazolopyridine derivatives (6, 8, 20, 28, and 42) were synthesized from 5-cyanomethyl-1,3-4-thiadiazole (1) and activated nitriles. Also, spiro indolono-thiadiazolopyridine (12) was obtained from the reaction of (1) with 2-(2-oxoi
- Elagamey,El-Taweel,Abu El-Enein
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p. 2155 - 2176
(2007/10/03)
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- The Reaction of Isothiocyanates with 2-Cyanoethanoic Acid Hydrazide. A Novel Synthesis of 1,3,4-Thiadiazoles
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Benzoyl and ethoxycarbonyl isothiocyanates reacted with 2-cyanoethanoic acid hydrazide 2 to afford 1-cyanoacetyl-4-substituted thiosemicarbazide (5a,b).Compound 5a afforded the pyrazolo-s-triazine derivative 6 on treatment with 5percent potassium h
- Elmoghayar, Mohamed Rifaat Hamza,Abdalla, Sanaa Osman,Nasr, Mohamed Yousry Abdel-Samad
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p. 781 - 784
(2007/10/02)
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