933709-26-3

Basic information

• Product Name: 1-Phenyl-3-pyrrolidinecarboxylic acid
• Synonyms: 1-Phenyl-3-pyrrolidinecarboxylic acid;1-phenylpyrrolidine-3-carboxylic acid(WXC08552)
• CAS NO: 933709-26-3
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.22642
• Mol File: 933709-26-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Phenyl-3-pyrrolidinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-3-pyrrolidinecarboxylic acid(933709-26-3)
• EPA Substance Registry System: 1-Phenyl-3-pyrrolidinecarboxylic acid(933709-26-3)

Safety Data

• Hazardous Substances Data: 933709-26-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-Phenyl-3-pyrrolidinecarboxylic acid is used as a key intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure and potential biological activity make it a valuable component in the development of new medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 1-Phenyl-3-pyrrolidinecarboxylic acid serves as a building block for the creation of complex organic molecules. Its versatility in chemical reactions allows for the construction of a wide range of organic compounds.
Used in Drug Development:
PPAC is utilized in drug development as a potential biologically active molecule. Its properties are being explored for use in the creation of new drugs, particularly those targeting specific medical conditions or diseases.
Used in Research and Development:
In the research and development sector, 1-Phenyl-3-pyrrolidinecarboxylic acid is employed as a subject of study to understand its properties, reactivity, and potential applications in various chemical and biological processes. This research can lead to innovative applications and advancements in multiple industries.

Upstream product

• 62-53-3 aniline 
• 64320-92-9 methyl 5-oxo-1-phenylpyrrolidine-3-carboxylate 
• 39629-86-2 5-oxo-1-phenyl-3-pyrrolidinecarboxylic acid 
• 97-65-4 2-methylenesuccinic acid 
• 122079-53-2 methyl 1-phenylpyrrolidine-3-carboxylate 

Relevant articles and documents

1-CYANO-PYRROLIDINE DERIVATIVES AS DUB INHIBITORS

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30). The novel compounds have formula (I): (Formula (I)) or are pharmaceutically acceptable salts thereof, wherein: R1a, R1b, R1c, R1d, R1e and R1f each independently represent hydrogen, optionally substituted C1-C6 alkyl or optionally substituted C3-C4 cycloalkyl, or R1b and R1c together form an optionally substituted C3-C6 cycloalkyl ring, or R1d and R1e together form an optionally substituted C3-C6 cycloalkyl ring; R2 represents hydrogen or optionally substituted C1-C6 alkyl; A represents an optionally further substituted 5 to 10 membered monocyclic or bicyclic heteroaryl, heterocyclyl or aryl ring; L represents a covalent bond or linker; B represents an optionally substituted 3 to 10 membered monocyclic or bicyclic heterocyclyl, heteroaryl, cycloalkyl or aryl ring; and when -A-L-B is at position x attachment to A is via a carbon ring atom of A, and either: A cannot be triazolopyridazinyl, triazolopyridinyl, imidazotriazinyl, imidazopyrazinyl or pyrrolopyrimidinyl; or B cannot be substituted with phenoxyl; or B cannot be cyclopentyl when L is an oxygen atom.

INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES

This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterised by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds.