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93457-07-9

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Cyanothiophene derivatives, compositions containing such compounds and methods of use
The present invention addresses substituted cyanothiophene derivatives of the formula I: as well as compositions containing such compounds and methods of treatment. The compounds in the present invention are glucagon antagonists. The compounds block the a
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Page 20

(2010/02/06)

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Chemical Properties

Appearance/Colour :clear light yellow liquid after melting
Melting Point: 46.0 to 51.0 °C
Boiling Point: 269 °C at 760 mmHg
Flash Point:111.5 °C
Density: 1.27 g/cm³
Solubility:soluble in Methanol
Vapor Pressure: 0.00742mmHg at 25°C
Refractive Index: 1.5500 (estimate)
PSA: 17.07000
LogP: 3.12490

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