Discovery and structure - Activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors
Dipeptidyl peptidase IV (DPP4) inhibitors are emerging as a new class of therapeutic agents for the treatment of type 2 diabetes. They exert their beneficial effects by increasing the levels of active glucagon-like peptide-1 and glucose-dependent insulino
Pei, Zhonghua,Li, Xiaofeng,Von Geldern, Thomas W.,Longenecker, Kenton,Pireh, Daisy,Stewart, Kent D.,Backes, Bradley J.,Lai, Chunqiu,Lubben, Thomas H.,Ballaron, Stephen J.,Beno, David W. A.,Kempf-Grote, Anita J.,Sham, Hing L.,Trevillyan, James M.
p. 1983 - 1987
(2008/02/04)
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