Ruthenium half-sandwich complexes as protein kinase inhibitors: Derivatization of the pyridocarbazole pharmacophore ligand
A general route to ruthenium pyridocarbazole half-sandwich complexes is presented and applied to the synthesis of sixteen new compounds, many of which have modulated protein kinase inhibition properties. For example, the incorporation of a fluorine into t
Pagano, Nicholas,Maksimoska, Jasna,Bregman, Howard,Williams, Douglas S.,Webster, Richard D.,Xue, Feng,Meggers, Eric
p. 1218 - 1227
(2008/02/04)
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