93788-48-8

Basic information

• Product Name: 3-Butenoic acid, 2-diazo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (4-nitrophenyl)methyl ester
• CAS NO: 93788-48-8
• Molecular Formula: C17H23N3O5Si
• Molecular Weight: 377.472
• Mol File: 93788-48-8.mol

Chemical Properties

• CAS DataBase Reference: 3-Butenoic acid, 2-diazo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (4-nitrophenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butenoic acid, 2-diazo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (4-nitrophenyl)methyl ester(93788-48-8)
• EPA Substance Registry System: 3-Butenoic acid, 2-diazo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (4-nitrophenyl)methyl ester(93788-48-8)

Safety Data

• Hazardous Substances Data: 93788-48-8(Hazardous Substances Data)

Upstream product

• 619-73-8 4-nitrobenzyl chloride 
• 61312-84-3 4-nitrobenzyl 3-oxobutanoate 

Downstream Products

• 83997-55-1 2-Diazo-4-((2R,3R)-3-ethyl-4-oxo-azetidin-2-yl)-3-oxo-butyric acid 4-nitro-phenyl ester 

Relevant articles and documents

Six-Membered Cyclic Nitroso Acetals: Synthesis and Studies of the Nitrogen Inversion Process of N-Silyloxy-3,6-dihydro-2H-1,2-oxazines

Silyl nitronates undergo rhodium-catalyzed formal [3+3]-cycloaddition with enol diazoacetates to form N-silyloxy-3,6-dihydro-2H-1,2-oxazines. The scope of the reaction and the extent of the major side process were evaluated. A mechanistic scheme was propo

Atypical Carbapenem Antibiotics with Improved Activity Against Carbapenemase-Producing Acinetobacter baumannii

The following invention deals with the design, preparation, evaluation, and use of carbapenem antibiotics with improved activity, relative to current commercially available carbapenem antibiotics, against infections involving multidrug resistant, carbapen

Functionalizing the γ-position of α-diazo-β-ketoesters

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Process for preparing an enol silyl ether compound

A process for preparing an enol silyl ether compound from a diazoacetoacetic acid ester having the general formula (IV): STR1 wherein R1 is a lower alkyl group having 1 to 6 carbon atoms, phenyl group, a substituted phenyl group, an aralkyl group or allyl group, and R2, R3 and R4 are the same or mutually different and each is a lower alkyl group having 1 to 6 carbon atoms, which comprises reacting a diazoacetoacetic acid ester having the general formula (I): STR2 wherein R1 is the same as defined above, with a trialkylsilyl chloride having the general formula (II): STR3 wherein R2, R3 and R4 are the same as defined above, in an inert solvent in the presence of an organic base and an alkali halide having the general formula (III): wherein M is an alkaline metal and X is bromine atom or iodine atom. The desired compound is useful as an intermediate for synthesis of carbapenem β-lactam antibiotics.