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CAS

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94-15-5

Dimethocaine, also known as DMC or larocaine, is a synthetic compound with local anesthetic and stimulatory properties similar to those of cocaine. It is a 4-aminobenzoic acid ester that resembles the structure of procaine and was used in the 1930s for its local anesthetic effects in dentistry and ophthalmology. Despite being addictive due to its stimulation of the reward pathway in the brain, dimethocaine is a legal cocaine replacement in some countries and is listed by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) under the category "synthetic cocaine derivatives."

94-15-5 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.
  • 94-15-5 Structure

  • Basic information

    1. Product Name: Dimethocaine
    2. Synonyms: Dimethocaine;3-(Diethylamino)-2,2-dimethyl-1-propanol p-aminobenzoate;Larocaine;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl ester;(3-Diethylamino-2,2-dimethyl)propyl 4-aminobenzoat;1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate (ester) (9ci);1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate
    3. CAS NO:94-15-5
    4. Molecular Formula: C16H26N2O2
    5. Molecular Weight: 278.44
    6. EINECS: 1592732-453-0
    7. Product Categories: chemical research;medicine grade;pharmaceutical intermediate
    8. Mol File: 94-15-5.mol

  • Chemical Properties

    1. Melting Point: 53.0 to 57.0 °C
    2. Boiling Point: 421.21°C (rough estimate)
    3. Flash Point: 197.8 °C
    4. Appearance: /
    5. Density: 1.035
    6. Vapor Pressure: 1.01E-06mmHg at 25°C
    7. Refractive Index: 1.5290 (estimate)
    8. Storage Temp.: Refrigerator
    9. Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
    10. PKA: 10.08±0.25(Predicted)
    11. Merck: 14,3221
    12. CAS DataBase Reference: Dimethocaine(CAS DataBase Reference)
    13. NIST Chemistry Reference: Dimethocaine(94-15-5)
    14. EPA Substance Registry System: Dimethocaine(94-15-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS: UB1575000
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 94-15-5(Hazardous Substances Data)

94-15-5 Usage

Uses

Used in Medical Applications:
Dimethocaine is used as a local anesthetic for various medical procedures, offering half the potency of cocaine. It is administered intravenously or nasally to avoid rapid hydrolysis that would occur with ingestion. The drug provides positive effects such as euphoria, stimulation, increased talkativeness, and mood lift.

Biological Activity

Dimethocaine is a local anesthetic that, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.

Check Digit Verification of cas no

The CAS Registry Mumber 94-15-5 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 94-15:
(4*9)+(3*4)+(2*1)+(1*5)=55
55 % 10 = 5
So 94-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H

94-15-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Propanol, 2-[(diethylamino)methyl]-2-methyl-, 1-(4-aminobenzoate)

1.2 Other means of identification

Product number -
Other names 3-Diethylamino-2,2-dimethylpropyl 4-aminobenzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94-15-5 SDS

94-15-5Upstream product

94-15-5Downstream Products