ENZYLATICALLY CLEAVABLE ALKOXYCARBONYL ETHOXYMETHYL ESTERS FOR REVERSIBLE BLOCKING OF CARBOXYL GROUPS
By O-alkylation carboxylic acids with α-bromo-α-ethoxy acetates new alkoxycarbonyl ethoxymethyl esters (ACEM esters) were synthesised in a simple route.The ACEM blocking group can be casily cleft by esterases.
Klemm, D.,Geschwend, G.
p. 2337 - 2348
(2007/10/02)
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