A concise synthesis of enantioenriched fluorinated carbocycles
(Chemical Equation Presented) A "reverse" cycloaddition- fluorination strategy has been validated to access enantioenriched fluorinated compounds featuring up to five stereogenic centers, one of which is fluorinated. This highly convergent process feature
Lam, Yu-Hong,Bobbio, Carla,Cooper, Ian R.,Gouverneur, Veronique
p. 5106 - 5110
(2008/09/16)
Fluorination process
Compounds of formula (II), (IIIa) or (IIIb) (variables are described in the specification) are prepared by fluorination of β,γ-unsaturated alkyl silanes. These compounds are useful as building blocks in the pharmaceutical industry.
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Page/Page column 39
(2008/06/13)
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