- ALPHA HELIX MIMETICS AND METHODS RELATING THERETO
-
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a chemical library relating thereto, and methods relating thereto, are disclosed. Applications of these compounds in the treatment of medical conditions, e.g., cancer diseases, fibrotic diseases, and pharmaceutical compositions comprising the mimetics are further disclosed.
- -
-
Page/Page column 120
(2010/11/18)
-
- Synthesis of praziquantel via N-acyliminium ion cyclization of amtoo acetals through several synthetic routes
-
Syntheses of praziquantel have been accomplished via an N-acyliminium ion by several routes including the tandem nucleophilic addition-cyclization sequence from amido acetal (8) or (10) and a stepwise cyclization of enamide (9) generated from the nucleophilic addition reaction of amido acetal (8) or (10).
- Kim, Joong Hyup,Lee, Yong Sup,Kim, Choong Sup
-
p. 2279 - 2285
(2007/10/03)
-