Welcome to LookChem.com Sign In|Join Free

CAS

  • or
1,3-Benzodioxole, 5-broMo-6-iodo- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

94670-76-5 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 94670-76-5 Structure
  • Basic information

    1. Product Name: 1,3-Benzodioxole, 5-broMo-6-iodo-
    2. Synonyms: 1,3-Benzodioxole, 5-broMo-6-iodo-;5-BROMO-6-IODO-BENZO(1,3)DIOXOLE;5-Bromo-6-iodobenzo[d][1,3]dioxole
    3. CAS NO:94670-76-5
    4. Molecular Formula: C7H4BrIO2
    5. Molecular Weight: 326.91393
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 94670-76-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 1,3-Benzodioxole, 5-broMo-6-iodo-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1,3-Benzodioxole, 5-broMo-6-iodo-(94670-76-5)
    11. EPA Substance Registry System: 1,3-Benzodioxole, 5-broMo-6-iodo-(94670-76-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 94670-76-5(Hazardous Substances Data)

94670-76-5 Usage

Chemical Structure

1,3-Benzodioxole, 5-bromo-6-iodo-

Derivative of Benzodioxole

Yes

Explanation

1,3-Benzodioxole, 5-bromo-6-iodois a derivative of the parent compound benzodioxole, which means it has a similar structure but with additional functional groups (in this case, bromine and iodine atoms).

Explanation

The compound contains both bromine and iodine atoms, which are halogens. These atoms can participate in various chemical reactions and contribute to the compound's unique properties.

Explanation

Due to its unique structure and properties, 1,3-Benzodioxole, 5-bromo-6-iodois used in various fields, including the synthesis of organic compounds, research in the pharmaceutical industry, and the production of industrial chemicals.

Explanation

The presence of bromine and iodine atoms in the compound allows it to be used as a building block for the creation of more complex chemical compounds, which can have a wide range of applications in different industries.

Explanation

The presence of both bromine and iodine atoms in the compound gives it unique properties, such as reactivity, stability, and solubility, which can be exploited in various chemical reactions and applications.

Presence of Halogen Atoms

Bromine and Iodine

Applications

Organic synthesis, pharmaceutical research, and industrial chemical production

Building Block for Complex Compounds

Yes

Unique Properties

Influenced by bromine and iodine atoms

Check Digit Verification of cas no

The CAS Registry Mumber 94670-76-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,6,7 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 94670-76:
(7*9)+(6*4)+(5*6)+(4*7)+(3*0)+(2*7)+(1*6)=165
165 % 10 = 5
So 94670-76-5 is a valid CAS Registry Number.

94670-76-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-6-iodo-1,3-benzodioxole

1.2 Other means of identification

Product number -
Other names 4,5-methylenedioxy-2-iodobromobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94670-76-5 SDS

94670-76-5Relevant articles and documents

Asymmetric C–H activation as a modern strategy towards expedient synthesis of steganone

Dherbassy, Quentin,Wencel-Delord, Joanna,Colobert, Fran?oise

, p. 5238 - 5245 (2016)

A formal synthesis of (+)-steganone by means of atroposelective C–H activation is reported. The herein described strategy is very straightforward as the targeted scaffold is afforded in only 10 steps, amongst which five of them are conducted without isola

Heteroatom-containing novel high B-ring berberine analogues and C-H activation synthesis method thereof

-

Paragraph 0011; 0014-0015, (2020/11/02)

The invention provides a heteroatom-containing novel high B-ring berberine analogue and a C-H activation synthesis method thereof. The novel high-B-ring berberine analogue with the potential p300 histone acetyltransferase inhibitory activity is prepared f

Fused Amino Pyridines for the Treatment of Lung Cancer

-

Paragraph 0149, (2016/11/17)

The present invention relates to the use of compounds with fused amino pyridine core for the treatment of malignancies associated with brain and lung. The oral administration of compounds of the instant application results in effective brain penetration and provides for non-intrusive treatment of brain and lung tumors.

Access to Atropisomerically En-riched Biaryls by the Coupling of Aryllithiums with Arynes under Control by Homochiral Oxazolines

Yalcouye, Boubacar,Berthelot-Bréhier, Ana?s,Augros, David,Panossian, Armen,Choppin, Sabine,Chessé, Matthieu,Colobert, Fran?oise,Leroux, Frédéric R.

supporting information, p. 725 - 732 (2017/01/18)

We report the preparation of axially stereoenriched biphenyls by the coupling of in situ generated aryllithiums and arynes using chiral oxazoline auxiliaries. The design of the aryne precursors, the choice of oxazoline and the reaction conditions were key to accessing the desired, highly substituted, atropisomerically enriched biarylic products. In one case, the two atropo-diastereomers could be obtained in isomerically pure form by column chromatographic separation and their absolute configurations established by X-ray crystallography. The stereoselectivity of the reaction seems to be governed by subtle parameters.

Atropo-diastereoselective coupling of aryllithiums and arynes — variations around the chiral auxiliary

Augros, David,Yalcouye, Boubacar,Berthelot-Bréhier, Ana?s,Chessé, Matthieu,Choppin, Sabine,Panossian, Armen,Leroux, Frédéric R.

, p. 5208 - 5220 (2016/08/02)

The atropo-selective coupling of in situ generated arynes and aryllithiums bearing various chiral auxiliaries ortho to lithium (tert-butylsulfoxide, para-tolylsulfoxide, tartrate-derived chiral diethers and oxazolines) is described. Chiral oxazolines showed the best results in terms of yields of coupling products. Different reaction parameters like the nature of the aryne precursor, the oxazoline, the alkyllithium base or the solvent revealed to be crucial for obtaining good yields and for diastereoselection.

FUSED AMINO PYRIDINES FOR THE TREATMENT OF BRAIN TUMORS

-

, (2010/08/07)

The present invention relates to the use of compounds with fused amino pyridine core for the treatment of malignancies associated with brain and lung. The oral administration of compounds of the instant application results in effective brain penetration and provides for non-intrusive treatment of brain and lung tumors.

HSP90 Inhibitors Containing a Zinc Binding Moiety

-

Page/Page column 36, (2008/12/08)

The present invention relates to HSP90 inhibitors and their use in the treatment of cell proliferative diseases such as cancer. The said derivatives may further act as HDAC inhibitors.

FUSED AMINO PYRIDINE AS HSP90 INHIBITORS

-

Page/Page column 38, (2008/12/08)

The present invention relates to HSP90 inhibitors containing fused amino pyridine core that are useful as inhibitors of HSP90 and their use in the treatment of HSP90 related diseases and disorders such as cancer, an autoimmune disease, or a neurodegenerative disease.

PtCl2-catalyzed hydrative cyclization of trialkyne functionalities to form bicyclic spiro ketones

Chang, Hsu-Kai,Datta, Swarup,Das, Arindam,Odedra, Arjan,Liu, Rai-Shung

, p. 4744 - 4747 (2008/02/08)

(Chemical Equation Presented) Triple rounds: A regioselective hydrative cyclization of triynes has been developed to give bicyclic β-hydroxy spiro ketones, which undergo subsequent dehydration to give the β,γ- unsaturated ketones (see scheme). Model reactions suggest that this platinum catalysis includes two selective hydrations, an alkyne insertion, and an aldol condensation.

Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90

He, Huazhong,Zatorska, Danuta,Kim, Joungnam,Aguirre, Julia,Llauger, Laura,She, Yuhong,Wu, Nian,Immormino, Robert M.,Gewirth, Daniel T.,Chiosis, Gabriela

, p. 381 - 390 (2007/10/03)

Hsp90 is a chaperone protein that allows cancer cells to tolerate the many components of dysregulated pathways. Its inactivation may result in targeting multiple molecular alterations and, thus, in reverting the transformed phenotype. The PU-class, a purine-scaffold Hsp90 inhibitor series, has been reported to be potent and selective against Hsp90 both in vitro and in vivo models of cancer. Here, a series of this class was synthesized and evaluated as inhibitors of the chaperone. The structure-activity relationship and selectivity for tumor Hsp90 of compounds within the series is presented. The study identifies water soluble derivatives (> 5 mM in PBS pH 7.4) of nanomolar potency (IC50 ~ 50 nM) in cellular and animal models of cancer. Binding affinities of these compounds for Hsp90 correlate well with their biological activities. When administered in vivo to mice bearing MDA-MB-468 human breast cancer xenografted tumors, these agents result in pharmacologically relevant concentrations and, accordingly, in modulation of Hsp90-client proteins in tumors.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 94670-76-5