948573-54-4 Usage
Uses
Used in Pharmaceutical Industry:
8-CHLORO-4-OXO-1,4-DIHYDRO-QUINOLINE-7-CARBOXYLIC ACID METHYL ESTER is used as a key intermediate in the synthesis of novel drugs, particularly those with antibacterial or antimalarial properties. Its unique structure and potential biological activity make it an intriguing target for further research and development in the pharmaceutical field.
Used in Antibacterial Drug Development:
In the field of antibacterial drug development, 8-CHLORO-4-OXO-1,4-DIHYDRO-QUINOLINE-7-CARBOXYLIC ACID METHYL ESTER is used as a precursor for the synthesis of new antibiotics. Its chemical structure may contribute to the development of drugs that can effectively target and eliminate bacteria, addressing the growing issue of antibiotic resistance.
Used in Antimalarial Drug Development:
8-CHLORO-4-OXO-1,4-DIHYDRO-QUINOLINE-7-CARBOXYLIC ACID METHYL ESTER is also used in the development of antimalarial drugs. Its potential biological activity and unique chemical structure make it a valuable compound for the creation of new treatments against malaria, a disease that continues to affect millions of people worldwide.
Check Digit Verification of cas no
The CAS Registry Mumber 948573-54-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,8,5,7 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 948573-54:
(8*9)+(7*4)+(6*8)+(5*5)+(4*7)+(3*3)+(2*5)+(1*4)=224
224 % 10 = 4
So 948573-54-4 is a valid CAS Registry Number.
948573-54-4Relevant articles and documents
Strategic studies in the syntheses of novel 6,7-substituted quinolones and 7- or 6-substituted 1,6- and 1,7-naphthyridones
Morgentin, Rémy,Pasquet, Georges,Boutron, Pascal,Jung, Frédéric,Lamorlette, Maryannick,Maudet, Micka?l,Plé, Patrick
, p. 2772 - 2782 (2008/09/19)
This paper describes the different strategies devised and applied to overcome the selectivity issues in the syntheses of 6,7-disubstituted-1H-quinolin-4-one, 7-substituted-1H-1,6-naphthyridin-4-one and 6-substituted-1H-1,7-naphthyridin-4-one derivatives. They allowed us to improve the overall yields and the scaling-up feasibility. Several examples illustrate these strategies with their advantages and drawbacks.
QUINOLINE DERIVATIVES
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Page/Page column 176, (2008/06/13)
The invention concerns quinoline derivatives of Formula (I): or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.
