Reductive cyclization of o-nitrophenyl propargyl alcohols: Facile synthesis of substituted quinolines
Reduction of secondary and tertiary o-nitrophenyl propargyl alcohols followed by acid-catalyzed Meyer-Schuster rearrangement gave 2-substituted and 2,4-disubstituted quinolines, respectively. Tertiary propargyl alcohols gave excellent yields of the quinoline derivative, while the yields of quinolines were slightly reduced when secondary propargyl alcohol derivatives were utilized.
Improved synthesis of cyclohexane-backbone iridium-complexes of quinoline-phosphine and their applications in asymmetric hydrogenation
– The iridium-complexes 3 and 4 with cyclohexane-backbone derived from quinoline were easily synthesized. The key step is cis/trans stereoselective reduction of 2-(quinolin-2-yl)cyclohexanone 5 to trans-2-(quinolin-2-yl)cyclohexanol 6 using Al(Oi-Pr)3/i-P
Liu, Qibin
(2020/09/15)
Red phosphorescence compounds and organic light-emitting device applying the compounds
Red phosphorescence compounds and an organic light-emitting device applying the compounds are disclosed. The general structure formula of the compounds is shown as I, wherein a structure shown in thedescription represents a structure shown in the descript
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(2019/03/10)
Intramolecular Desulfitative Coupling: Nickel-Catalyzed Transformation of Diaryl Sulfones into Biaryls via Extrusion of SO2
As a new transformation of organosulfur compounds, intramolecular desulfitative coupling of diaryl sulfones to the corresponding biaryls has been developed with the aid of nickel-NHC catalysts. This catalytic elimination of SO2 was also applicable to alkenyl aryl sulfone to furnish the corresponding alkenyl arene.
Takahashi, Fumiya,Nogi, Keisuke,Yorimitsu, Hideki
p. 6601 - 6605
(2018/10/20)
Facile synthesis of 2-substituted quinolines and 3-alkynyl-2-aryl-2H-Indazole via SnCl2-mediated reductive cyclization
A rapid and efficient SnCl2·2H2O mediated synthesis of quinolines and indazoles has been developed using A3-coupling followed by reductive cyclization. The key highlights are the formation of quinoline in a one-pot fashion and indazole through N-N bond formation.