Bredt's Rule. Part 6. The Synthesis of 5-Phenyl-1-azabicyclononan-2-one, a Bridgehead Amide
6-Oxo-3-phenylpiperidine-3-propanoic acid, prepared from dimethyl 4-cyano-4-phenylheptanedioate, has been reduced selectively to the corresponding amine and then cyclised thermally or via its acid chloride to 5-phenyl-1-azabicyclononan-2-one.
Buchanan, George L.
p. 2669 - 2670
(2007/10/02)
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