- Potential Antimalarials. VII. Di-Mannich Bases of 4-aminophenol via 4-Nitrophenols
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A series of di-Mannich bases have been prepared from 4-nitrophenol and paraformaldehyde with dimethylamine, diethylamine, dipropylamine, N-(2'-hydroxyethyl)methylamine, piperidine, 3- and 4-methylpiperidine, 3,5-dimethylpiperidine or pyrrolidine.These nit
- Barlin, Gordon B.,Ireland, Stephen J.
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p. 1727 - 1734
(2007/10/02)
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- Phthalazine compounds, compositions and use
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The present invention relates to new compounds of the formula STR1 alkylene, or --S-- where R1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y)A is --CH2 NR2/s
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- Synthesis and Antiarrhythmic and Parasympatholytic Properties of Substituted Phenols. 1. Heteroarylamine Derivatives
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Twenty-four structural derivatives of the antiarrhythmic drug changrolin were synthesized and tested for antiarrhythmic and parasympatholytic activities.It was found that while the bis(pyrrolidinylmethyl)phenol pattern of changrolin appeared to be optimal
- Stout, David M.,Matier, W. L.,Barcelon-Yang, Cynthia,Reynolds, Robert D.,Brown, Barry S.
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p. 808 - 813
(2007/10/02)
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