- CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
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Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
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- NEW CHEMICAL COMPOUNDS
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The present invention encompasses compounds of general formula (1) while the groups R4 to R7 and the units W, L, Qa and QH are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use as medicaments having the above-mentioned properties.
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Page/Page column 78-79
(2010/04/03)
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- NEW CHEMICAL COMPOUNDS
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The present invention encompasses compounds of general formula (1) wherein the units W, A, L, Q1 and QH are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use as medicaments having the above-mentioned properties.
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Page/Page column 112
(2010/04/03)
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- QUINAZOLINES FOR PDK1 INHIBITION
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The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
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Page/Page column 308
(2008/06/13)
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