- Acid- and base-stable esters: A new protecting group for carboxylic acids
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An acid- and base-stable protecting group for carboxylic acids is described. The esters of (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl) methanol are stable to Bransted and Lewis acids, Bronsted bases, and a wide variety of nucleophiles; however, the esters can be conveniently deprotected by a solvolytic displacement reaction with 20% trifluoroacetic acid. Georg Thieme Verlag Stuttgart.
- Kurosu, Michio,Biswas, Kallolmay,Narayanasamy, Prabagaran,Crick, Dean C.
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p. 2513 - 2516
(2008/02/13)
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