955403-51-7

Basic information

• Product Name: Benzenepropanal, 3-fluoro-4-Methyl- (or 3-(3-Fluoro-4-Methylphenyl)propionaldehyde )
• Synonyms: Benzenepropanal, 3-fluoro-4-Methyl- (or 3-(3-Fluoro-4-Methylphenyl)propionaldehyde );3-(3-fluoro-4-methylphenyl)propanal
• CAS NO: 955403-51-7
• Molecular Formula: C₁₀H₁₁FO
• Molecular Weight: 166.1921432
• Mol File: 955403-51-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanal, 3-fluoro-4-Methyl- (or 3-(3-Fluoro-4-Methylphenyl)propionaldehyde )(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanal, 3-fluoro-4-Methyl- (or 3-(3-Fluoro-4-Methylphenyl)propionaldehyde )(955403-51-7)
• EPA Substance Registry System: Benzenepropanal, 3-fluoro-4-Methyl- (or 3-(3-Fluoro-4-Methylphenyl)propionaldehyde )(955403-51-7)

Safety Data

• Hazardous Substances Data: 955403-51-7(Hazardous Substances Data)

Upstream product

• 39998-81-7 2-fluoro-4-iodotoluene 
• 107-18-6 allyl alcohol 

Downstream Products

• 923133-90-8 C₁₁H₁₁FN₂S 

Relevant articles and documents

PYRAZOLO-TETRAHYDROPYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to novel pyrazolo-tetrahydropyridines compounds and their use as orexin receptor antagonists.

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide

A series of structurally novel stearoyl-CoA desaturase-1 (SCD-1) inhibitors has been identified by optimizing a hit from our corporate library. Preliminary structure-activity relationship (SAR) studies led to the discovery of the highly potent and orally bioavailable thiazole-based SCD-1 inhibitor, 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide (23a).

PYRAZOLO-TETRAHYDRO PYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to novel pyrazolo-tetrahydropyridines compounds and their use as orexin receptor antagonists.

5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES

The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I),wherein X represents CH2 or O; R1 represents a phenyl group, which group is independently mono-, di-, or tri-substituted wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, halogen, cyano, trifluoromethoxy and trifluoromethyl; R2 represents (C1-4)alkyl, (C1-4)alkoxy, (C2-4)alkenyl, halogen, cyano, hydroxymethyl, trifluoromethyl, C(O)NR5R6 or cyclopropyl; R3 represents (C1-4)alkyl, (C1-4)alkoxy-methyl or halogen; R4 represents (C1-4)alkyl; R5 represents hydrogen or (C1-4)alkyl; and R6 represents hydrogen or (C1-4)alkyl. The invention also relates to pharmaceutically acceptable salts of such compounds; and to the use of such compounds as medicaments; especially as orexin receptor antagonists.