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N2-Isobutyryl-7'-OH-morpholino guanosine is a modified nucleoside derived from the morpholino class. It is characterized by the presence of an isobutyryl group at the N2 position and a hydroxyl group at the 7' position. This unique structure allows it to be incorporated into oligonucleotide sequences, which can be spliced into a genome to achieve gene silencing.

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  • N-(9-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

    Cas No: 956139-23-4

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  • N-(9-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

    Cas No: 956139-23-4

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  • 956139-23-4 Structure
  • Basic information

    1. Product Name: N2-Isobutyryl-7'-OH-Morpholino guanosine
    2. Synonyms: N2-Isobutyryl-7'-OH-Morpholino guanosine;N-[6,9-dihydro-9-[(2R,6S)-6-(hydroxyMethyl)-2-Morpholinyl]-6-oxo-1H-purin-2-yl]-2-Methyl-PropanaMide
    3. CAS NO:956139-23-4
    4. Molecular Formula: C14H20N6O4
    5. Molecular Weight: 336.3464
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 956139-23-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N2-Isobutyryl-7'-OH-Morpholino guanosine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N2-Isobutyryl-7'-OH-Morpholino guanosine(956139-23-4)
    11. EPA Substance Registry System: N2-Isobutyryl-7'-OH-Morpholino guanosine(956139-23-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 956139-23-4(Hazardous Substances Data)

956139-23-4 Usage

Uses

Used in Gene Silencing Applications:
N2-Isobutyryl-7'-OH-morpholino guanosine is used as a gene-silencing agent in the field of molecular biology and genetics. It is incorporated into oligonucleotide sequences that, when spliced into a genome, can effectively silence specific genes. This property makes it a valuable tool for studying gene function and developing targeted therapies for various diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N2-Isobutyryl-7'-OH-morpholino guanosine is used as a key component in the development of antisense drugs. These drugs work by binding to specific RNA sequences, preventing their translation into proteins, and thus modulating gene expression. This approach has the potential to treat a wide range of genetic disorders and diseases by targeting the underlying genetic causes.
Used in Research and Development:
N2-Isobutyryl-7'-OH-morpholino guanosine is also used in research and development for the study of gene regulation and the development of new therapeutic strategies. Its ability to silence genes makes it a valuable tool for understanding the roles of specific genes in various biological processes and for identifying potential drug targets.
Overall, N2-Isobutyryl-7'-OH-morpholino guanosine is a versatile and promising molecule with applications in gene silencing, pharmaceutical development, and research, making it an important asset in the fields of molecular biology, genetics, and medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 956139-23-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,6,1,3 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 956139-23:
(8*9)+(7*5)+(6*6)+(5*1)+(4*3)+(3*9)+(2*2)+(1*3)=194
194 % 10 = 4
So 956139-23-4 is a valid CAS Registry Number.

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