Disclosed herein are phosphorothioate nucleotide analogs, methods of synthesizing phosphorothioate nucleotide analogs and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with the phosphorothioate
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Page/Page column 111
(2012/04/04)
2′-C-alkylribonucleosides: Design, synthesis, and conformation
Certain 2′-C-alkylribonucleotides have been designed as potential mechanism-based inactivators of ribonucleotide reductases. A short, flexible route toward the corresponding nucleosides and NMR evidence concerning their preferred solution conformations are discussed. Copyright
Harry-O'kuru, Rogers E.,Kryjak, Emily A.,Wolfe, Michael S.
p. 1457 - 1460
(2007/10/03)
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