Solid-phase based synthesis of jasplakinolide analogs by intramolecular azide-alkyne cycloadditions
The synthesis of a focused library of jasplakinolide analogs with a 1,2,3-triazole in place of an E-configured double bond is described, featuring the Cu(i) catalyzed azide-alkyne cycloaddition reaction as an efficient macrocyclization tool. The Royal Society of Chemistry.
Hu, Tai-Shan,Tannert, Rene,Arndt, Hans-Dieter,Waldmann, Herbert
p. 3942 - 3944
(2008/09/21)
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