95849-26-6

Basic information

• Product Name: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde
• Synonyms: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde;(1,4-Dioxolo[2,3-b]pyridine-7-carboxaldehyde,2,3-dihydro-)
• CAS NO: 95849-26-6
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.147
• Mol File: 95849-26-6.mol

Chemical Properties

• Boiling Point: 317.198ºC at 760 mmHg
• Flash Point: 145.637ºC
• Appearance: /
• Density: 1.34g/cm3
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde(95849-26-6)
• EPA Substance Registry System: 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde(95849-26-6)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 95849-26-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde is used as a key intermediate in the synthesis of complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the development of new compounds with potential applications in various fields.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde is utilized as a building block for the synthesis of biologically active molecules. Its incorporation into drug candidates can potentially enhance their therapeutic effects and selectivity.
Used in Anti-inflammatory Applications:
2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde is studied for its potential as an anti-inflammatory agent. It may be used to modulate inflammatory pathways and reduce the symptoms associated with inflammatory diseases, although further research is required to confirm its efficacy and safety in this context.
Used in Anti-cancer Applications:
2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde is also being investigated for its potential as an anti-cancer agent. It may contribute to the development of novel therapeutics that target cancer cells, inhibiting their growth and proliferation. The exact mechanisms of action and the extent of its anti-cancer properties are subjects of ongoing research.

InChI:InChI=1/C8H7NO3/c10-5-6-3-7-8(9-4-6)12-2-1-11-7/h3-5H,1-2H2

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 95897-49-7 7-Brom-pyrido<2,3-b><1,4>dioxen 
• 34206-49-0 5-bromo-2,3-dihydroxy-pyridine 

Relevant articles and documents

DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF

The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to a pharmaceutical composition and formulation containing a derivative of piperlongumine; and use of the derivatives and analogs for treating cancer, reducing inflammation and/or treating an autoimmune or inflammatory disease.

DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF

The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3- dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to processes for preparing the same; a pharmaceutical composition and formulation containing a derivative of piperlogumine; and use of the derivatives and analogs for treating cancer.

AMINOCYCLOHEXENE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY

Cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.

NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS

Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.