Synthesis and biological evaluation of l- and d-configurations of 2′,3′-dideoxy-4′-c-methyl-3′-oxacytidine analogues
Novel L- and D-configuration 2′,3′-dideoxy-4′-C-methyl-3′-oxacytidine and their 5-fluoro analogues have been synthesized from 1-benzyloxy-2-propanone and L-ascorbic acid in eight steps and evaluated for biological activity.
Liu, Mao-Chin,Luo, Mei-Zhen,Mozdziesz, Diane E.,Lin, Tai-Shun,Dutschman, Ginger E.,Gullen, Elizabeth A.,Cheng, Yung-Chi,Sartorelli, Alan C.
p. 2301 - 2304
(2007/10/03)
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