959918-19-5

Basic information

• Product Name: 3-Ethynylpiperidine hydrochloride
• Synonyms: 3-Ethynylpiperidine hydrochloride;Piperidine, 3-ethynyl-, hydrochloride (1:1);3-ETHYNYLPIPERIDINE HCL
• CAS NO: 959918-19-5
• Molecular Formula: C₇H₁₁N*ClH
• Molecular Weight: 145.63
• Mol File: 959918-19-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Ethynylpiperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethynylpiperidine hydrochloride(959918-19-5)
• EPA Substance Registry System: 3-Ethynylpiperidine hydrochloride(959918-19-5)

Safety Data

• Hazardous Substances Data: 959918-19-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Ethynylpiperidine hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds for its potential role in the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 3-Ethynylpiperidine hydrochloride serves as a valuable compound for studying the properties and reactions of aralkylamines, contributing to the advancement of organic chemistry.
Used in Organic Synthesis:
3-Ethynylpiperidine hydrochloride is utilized as a building block in organic synthesis, enabling the creation of a range of organic molecules for various applications, including the development of new materials and compounds.

Upstream product

• 664362-16-7 tert-butyl 3-ethynylpiperidine-1-carboxylate 

Relevant articles and documents

Development of a selective activity-based probe for glycosylated LIPA

Loss of LIPA activity leads to diseases such as Wolman's Disease and Cholesterol Ester Storage Disease. While it is possible to measure defects in LIPA protein levels, it is difficult to directly measure LIPA activity in cells. In order to measure LIPA activity directly we developed a LIPA specific activity based probe. LIPA is heavily glycosylated although it is unclear how glycosylation affects LIPA activity or function. Our probe is specific for a glycosylated form of LIPA in cells, although it labels purified LIPA regardless of glycosylation.

FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS

A series of 5,6-dihydro-1-benzothiophen-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.