Regioselective C-4 bromination of oxazoles: 4-bromo-5-(thiophen-2-YL) oxazole
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Li, Bryan,Buzon, Richard A.,Zhang, Zhijun,Koshiba, Takahiro,Fukuyama, Tohru
p. 16 - 25
(2011/05/07)
Syntheses of 4,5-disubstituted oxazoles via regioselective C-4 bromination
A scaleable and highly regioselective C-4 bromination of 5-substituted oxazoles is described. The use of DMF as solvent played a critical role in significantly improving the C-4/C-2 bromination ratio. The resulting 4-bromooxazoles were shown to be good Su
Li, Bryan,Buzon, Richard A.,Zhang, Zhijun
p. 951 - 955
(2012/12/30)
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