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960404-86-8

Dapagliflozin Impurity 10, also known as Dapagliflozin Hydroxy Impurity, is an impurity of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor. It is a pharmaceutical compound that is used in the synthesis and manufacturing process of Dapagliflozin, a medication used to treat type 2 diabetes.
Used in Pharmaceutical Industry:
Dapagliflozin Impurity 10 is used as a reference standard for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity, potency, and safety of Dapagliflozin, a medication used to treat type 2 diabetes.
Used in Research and Development:
Dapagliflozin Impurity 10 is used as a research tool in the development of new drugs and therapies for diabetes. It aids in understanding the mechanism of action, side effects, and potential interactions with other medications.
Used in Regulatory Compliance:
Dapagliflozin Impurity 10 is used to meet regulatory requirements for drug approval and post-marketing surveillance. It helps ensure that Dapagliflozin meets the necessary safety and efficacy standards for use in patients.

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  • 960404-86-8 Structure

  • Basic information

    1. Product Name: Dapagliflozin Impurity 10
    2. Synonyms: Dapagliflozin Impurity 10
    3. CAS NO:960404-86-8
    4. Molecular Formula: C21H25ClO7
    5. Molecular Weight: 424.87
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 960404-86-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 618.3±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.423±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 11.10±0.70(Predicted)
    10. CAS DataBase Reference: Dapagliflozin Impurity 10(CAS DataBase Reference)
    11. NIST Chemistry Reference: Dapagliflozin Impurity 10(960404-86-8)
    12. EPA Substance Registry System: Dapagliflozin Impurity 10(960404-86-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 960404-86-8(Hazardous Substances Data)

960404-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 960404-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,6,0,4,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 960404-86:
(8*9)+(7*6)+(6*0)+(5*4)+(4*0)+(3*4)+(2*8)+(1*6)=168
168 % 10 = 8
So 960404-86-8 is a valid CAS Registry Number.

960404-86-8Relevant articles and documents

PROCESS FOR THE PREPARATION OF DAPAGLIFLOZIN AND ITS SOLVATE THEREOF

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Page/Page column 17, (2018/04/11)

The present invention provides for crystalline Dapagliflozin butane –1,2– diol solvate (VIII), crystalline Dapagliflozin (S) butane –1,2– diol solvate (VIIIa) and Dapagliflozin (R) butane –1,2– diol solvate (VIIIb). The present invention also provides industrial methods for production of crystalline Dapagliflozin butane –1,2– diol solvate (VIII), crystalline 5 Dapagliflozin (S) butane –1,2– diol solvate (VIIIa) and Dapagliflozin (R) butane –1,2– diol solvate (VIIIb). The present invention further provides an industrial method production of amorphous Dapagliflozin.

PROCESS FOR THE PREPARATION OF BENZYLBENZENE SGLT2 INHIBITORS

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Page/Page column 0321-0329, (2013/10/22)

Provided are methods of making compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides synthetic intermediates useful for preparing such compounds.

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